Tuesday, June 4, 2019
Non-communicable diseases Diseases of Excess
Non-communicable disorders Diseases of ExcessNon-Communicable diseases often referred to as Diseases of Excess or Diseases of Affluence atomic proceeds 18 increasing in both rich and poor countries. What agentive components be contri unlessing to this trend? What atomic number 18 the implications for public wellness policy?Health is a state of complete physical, genial and social well-being and non merely the absence of disease or infirmity (WHO, 1948) where as Disease is a condition where any deviation from or interruption of the normal structure or function of any body part, organ, or system that is manifested by a characteristic set of symptoms and signs and whose etiology, pathology, and prognosis may be know or unkn give birth (Dorlands Medical Dictionary, 2007). Disease atomic number 50 be divided b highroadly into two categories as Communicable and Non Communicable Diseases (on the creation of its spread). Communicable disease is a disease which can spread from atomic number 53 individual to other finished any carrier/organism (Malaria, HIV/AIDS, and so forth. It is in addition known as Infectious or Contagious disease. There ar many parts responsible for the cause of communicable diseases wish social, environmental, sanitation and education. Non Communicable disease is a disease which is not communicated from one individual from another (Hypertension, genus Cancer, etc). It is too known as Chronic diseases because these diseases takes lot of time to show the sign and symptoms at heart an individual. The study causes for NCDs are lifestyle, robess like smoking and alcohol, in equal to(predicate) diet and physical inactivity.Communicable diseases was account to be the major cause of demise in ahead time where as Non Communicable diseases(NCDs) are of major threat in current era except in some countries like Africa where motionlessness bulk die issue of infections. In some countries like USA, the spark advance cause of la st in 1900s was tuberculosis and pneumonia where as these diseases are secondary nowadays and their places are acquired by the cardiovascular diseases on the top and malignant neoplastic disease being the second. The main reason for the reduction in communicable diseases are the correctment in diagnosis, treatment, sanitation, nutrition, housing, fiting conditions, preventive measures such as immunization, evolution of life saving drugs like antibiotics and sulpha drugs.Non-Communicable diseases or Non-Infectious diseases are caused by factors mainly behavioural, lifestyle and heredity and which cannot be transmitted to other individual. It is besides caused as the Disease of Affluence or the Disease of Excess as it is caused due to negligence or disturbance caused in the normal routine lifestyle which is mainly found in the upper class of the society where there is more chances of misbalance between diet and work can be seen. Few of the slips which come under non communicable diseases are Heart diseases, Stroke, Obesity, Diabetes, Cancer, etc. Acc. to WHOs statistics in 2008, Heart Stroke has become the leading cause of death glob on the wholey leaving behind the infectious diseases like HIV/AIDS, TB, Malaria, etc.In 2003, there was an estimated 56 one thousand thousand death globally, out of which 60% death was supposed to be due to non-communicable diseases (WHO, 2003). Among NCDs, 16 million deaths resulted from cardiovascular disease (CVD), especially Coronary Heart Disease (CHD) and Stroke 7 million from Cancer 35 million from Chronic Respiratory Disease and almost 1 million from Diabetes (Ibid). Apart from these, mental health problems are also the leading contributors to the payload of disease in many countries nowadays and play a major role in contributing to the severity and incidence of other NCDs.NCDs are now considered to be the major threat contributing 59% of death in 2000 and predicted to account for 73% by 2020 (WHO, 2002). NCDs are also circumstanceed as a Disease of Affluence due to incidence and prevalence mainly in the developed countries (Anand K et al, 2007). But according to them, this seems to be a misleading term as the NCD trend is increasing at a mel number oneer pace in middle and low income countries leaving them in a bivalent burden of Communicable diseases as well as NCDs. It can more appropriately be labelled as Disease of Urbanisation (Ibid). Several studies done by them kick in proved that the NCDs and its risk factors are found in higher proportion among urban population than rural population. Their study shows that urban population has increase during past decade due to migration where as urban growth is stabilized at 3%. Contrary to it, the urban slum growth rate has multiply which has made the situation worse as these migrated poor people living in urban areas will adopt the NCD lifestyle but will not be in a condition to access the health trade due to their poor purchasing ability. Stu dy shows a high prevalence of NCDs risk factor in the urban slums of Haryana, India. The population residing in the slums is at high risk than the urban population due to poor access as well as no social and health support system for them. This requires an urgent encumbrance which can work at national, community as well as topical anaesthetic level. A framework of the policy is required at national level which has tobacco and alcohol control measures, promotion of good diet and involvement of square-toed exercise. Simultaneously, reorientation and strengthening of the administrations health system is needed to face the challenge of NCDs community level efforts to create an environment which promotes adoption of healthy behaviors. To overcome this situation, government has started the Integrated Disease Surveillance Programme (IDSP) which hand overs a rational basis for decision making and implementing public health interventions and also ensures involving the slums as well (Ibi d).A see was being conducted by Anand et al in urban areas slums of Faridabad District, Haryana, India, in February 2003 to June 2004 for checking out the prevalence of NCDs in urban poor people. Their study followed the STEPS climb of WHO where questions related to tobacco use, alcohol inhalation, diet, physical activity were holdd and history of treatment for hypertension, diabetes, physical values like height, weight, waist circumference and blood military press were also measured. They surveyed 1260 men and 1304 women of age 15-64. The result came out of this survey was real alarming. The rate of smoking and alcohol drinkers were high among urban slums male population. Almost one third of the population had at l eastward one risk factor. Alcohol consumption among younger population indicates gradually locomote economy of the country in the coming future.The table 1 (Appendix) shows that NCDs are the leading cause for the death in both developed and ontogeny countries exc ept some countries like Africa where thus far today, there is more number of death due to communicable diseases than NCDs. In 2003, 28 million CVD deaths occur in chinaware and 26 million in India. NCDs contributed substantially to adult mortality with central and eastern Europe having the highest rank (WHO, 2003).The Table 2 (Appendix) shows that the developed countries have seven NCDs out of ten leading risk factors which are contributing to the global burden of disease, where as six and three out of ten with low and high rates of mortality respectively, in the evolution countries. These NCD risk factors are increasing at a higher rate in the development countries and assumed to continue in the same manner for the next two decades.Chronic diseases attribute to the 46% of the global burden of the disease, Cardio Vascular Diseases (CVDs), in particular. Although some of the communicable diseases are still prominent in the some parts of the Africa, Asia and Latin America, deaths mainly due to chronic diseases were reported in five out of the six WHO regions (Africa, America, South east Asia, Eastern Mediterranean, Western Pacific and Europe). In developing countries also, 79% of the deaths are reported due to the chronic diseases. Incidence and prevalence of obesity, diabetes, cancers, respiratory diseases and other NCDs are increasing all over the world (Murray and Lopaz, 1996). Developing country like China has experienced an epidemiological changeover shifting from the infectious to the chronic diseases in much shorter time than many other countries. The pace and spread of behavioral changes, including changing diets, decreased physical activity, high rates of male smoking, and other high risk behaviors, has accelerated to an unprecedented degree. As a result, the burden of chronic diseases, preventable morbidity and mortality, and associated health-care costs could now increase substantially. China already has 177 million adults with hypertension furt hermore, 303 million adults smoke, which is a third of the worlds total number of smokers, and 530 million people in China are passively exposed to second-hand smoke. The prevalence of grueling people and obesity is increasing in Chinese adults and children, because of dietary changes and reduced physical activity. Emergence of chronic diseases presents special challenges for Chinas ongoing reform of health care, prone the large numbers who require curative treatment and the narrow window of opportunity for timely prevention of disease (Gonghuan Y et al, 2008).Common Non-Communicable Diseasescardiovascular diseases include all the heart diseases like hypertension, stroke, atherosclerosis, etc. Annually, 17 million deaths are reported mainly due to the CVDs globally out of which 80% are reported in low and middle income countries with a continuous increasing trend (Reddy and Yusuf, 1998). Acc. to Lenfant, CVD will be the leading cause of the death by 2010 in the developing countrie s due to changes brought about by urbanization and industrialization. Due to costly and pro pertinacioused treatment cost of CVDs, developing countries are at greater prevalence for the risk factors, higher incidence of disease and higher mortality (Reddy, 2002).Diabetes is increase in blood sugar level in a person. International Diabetes Federation has released the statistics in 2003, according to which diabetes patients will going to increase from 194 million in 2003 to 330 million in 2030 and at that time every 3 out of 4 living person will be diabetic. The age of diabetic patients in developing countries is comparatively more than developed countries. The cases found in developing countries are to a higher place the age of retirement which may lead to conditions like blindness, amputations, kidney failure and heart diseases (Boutayeb and Twizell, 2004).Cancer and its type are increasing at an alarming rate worldwide. It is known to be the major cause for the mortality and morbi dity. More than 10 million new cases and over 7 million deaths from cancer occurred in 2000 (Shibuya et al., 2002). Developing countries contributed by 53% in incidence and 56% in deaths. By 2020, there will be an increase of around 29% cases in developed countries and 73% in developing countries (Mathers et al., 1999). Lung, breast, stomach, colorectal and liver cancer are the most frequent in developing countries. Cancer and its related types can be tempered on a preventative basis. Early detection and control of risk factors like tobacco and alcohol can be said to be the cornerstones in this process because it is estimated that over one third of the cancer types are preventable and around one third are potentially curable if they are detect early (Alwan, 1997).Other NCDs includes chronic respiratory diseases like asthma and chronic obstructive pulmonary diseases, mental and depressive disorders, osteoarthritis, hearing loss and disorder of vision (WHO, 2003). They all contribute mainly to the burden of disease in developing countries. Conditions such as obesity and high blood pressure also has a double impingement, either as a disease or as a risk factor for other NCDs (WHO, 2004).Risk FactorsThe life expectancy at abide has increased since 1970 in all the high, middle and low income countries (UNDP, 2005). Due to this factor, longer life span has resulted in the predominance of the chronic diseases in the population. The epidemiological transition has resulted in the higher proportion of the adults population due to decline in fertility rates and the infant mortality rates. The behavioural risk factors like smoking and nutritional transition towards diet having high plonk, high sugar with low carbohydrates and fruits along with the physical inactivity and increase in alcohol consumption have become the greatest health challenge in the 21st century (Magnusson, 2007). The environmental causes are also responsible for the emergence of NCD as an epidemic. T hese factors have brought up the nutrition transition by industrialisation of the food production, expansion of the market economies in the developing countries, the growth of the complex supply chain management at a global level, rapid growth of supermarket in the developing world and the growing concentration of global food manufacturers (Ibid). Some other key factors like rising incomes, production of cheap and low energy-dense foods, growing urbanisation and increase in growth in demand for pre-packed food are also the major risk factors for NCDs (Ibid).The evolution of NCDs has put up a double burden on low and middle income countries. Diabetes and lung cancer are also reflecting rise in the rate of smoking and obesity which are called to be the major risk factors for the NCDs (Leeder, 2004). In the year 2001, 17 million people died due to heart diseases where as 3 million people died due to AIDS (Ibid). During this year, heart disease and stroke were the leading cause of death in both high income and low-middle income countries, account statement for 27 and 21% population respectively. Out of all, 83% of death occurred in the developing countries (Ibid). Evidence has shown that CVD occurs at an early age in developing countries, overpowering their productive years of life. Globally, obese people are also increasing at a higher pace with a far higher number overall in developing countries. Due to this, diabetic patients are also increasing with more number falling in the 45-65 age group (Ibid). tobacco causes 4.8 million premature deaths in the year 2000, half of which were in the developing world (Ezzati and Lopez, 2003). Since 1975, cigarette consumption has decreased sharply in the developed countries, but it is continuously rising in developing countries due to the rapid increase in population. More than 1 zillion smokers lives in the developing counties out of 1.3 billion smokers globally which indicates that forthcoming threat of tobacco related epidemic will impact the developing world. Even after non smoking awareness programme through out the world, there will be around 1.45 billion smokers in 2025 (Guindon and Boisclair, 2003). Tragically, half to two third of the chronic smokers will die out of their habit (Jamison et al, 2006). Peto and lopez has estimated that if this trend continues, 10 million people will die every year because of tobacco where 7 out of 10 will be from the developing countries resulting in around 150 million death till 2025.The ageing of populations, mainly due to falling fertility rates and increasing child survival, are an underlying determinant of non-communicable disease epidemics. Additionally, global trade and marketing developments are driving the nutrition transition towards diets with a high proportion of saturated fat and sugars. This diet, in combination with tobacco use and little physical activity, leads to population-wide atherosclerosis and the widespread distribution of non-communic able disease. Globally, many of the risk factors for heart disease, diabetes, cancer and pulmonary diseases are due to lifestyle and can be prevented. bodily inactivity, Western diet, alcohol and smoking are prominent causes for the NCDs and its risk factors.Tobacco is number one confrontation of public health (WHO, 2000). It is the most important established cause of cancer but also responsible in CVDs and chronic respiratory disease. In the 20th century, approximately 100 million people died worldwide from tobacco-associated diseases such as cancer, chronic lung disease, diabetes and CVDs. Half of the 5 million deaths attributed to smoking in 2000 occurred in developing countries where smoking prevalence among men is nearly 50%. Today, 80% of the 1.2 billion smokers in the world live in poorer countries and, while tobacco consumption is falling in most developed countries, it is increasing in developing countries by about 3.4% per annum. However, albeit these striking facts, th e majority of developing countries which signed the Framework prescript on Tobacco Control (FCTC) (Joossens, 2000) remain passive about the control of smoking.Obesity and dietary habits represent potential risk factors for CVDs (Kenchaiah et al., 2002), type 2 diabetes (Drewnowski and Specter, 2004), and some types of cancer (Key, 2002), especially in absence of physical activity (Derouich and Boutayeb, 2002 and WHO, 2003b). Fish is considered to be a useful food intake to prevent CVDs and reduction of CVD associated deaths (Stampfer, 2000). Similarly, intake of an adequate quantity of fresh fruit and vegetables is recommended to help reduce the risk of coronary disease, stroke and high blood pressure (WHO, 2002). But, developing countries finds it more fruitful to exporting most of the quality fruits and vegetable production in exchange of the foreign currency.Alcohol causes more than 2 million deaths every year in the world. It is in particular associated with liver disease and esophageal cancer. The increase in alcohol consumption in developing countries will add other hazards caused by violence and road accidents to the burden of disease.Public health policy and its implicationsLee, Fustukian and Buse provide a utile framework for disentangling four dimensions of global health policy-making (Lee et al, 2002) as-* Policy Actors They are the power (political) who can drive the policy and decision making at a global level. In case of NCDs, United Nations, WHO, FAO, WTO, World bank, Codex Alimentarius Commission, etc.* Policy Process Process through which policy is developed and utilise. Interactions and congenericship between policy actors.* Policy Context For NCDs, its global.* Policy Content Effective dodge should address universal prevention , selective or primary prevention for high risk group and targeted or secondary prevention and treatment for those with alive conditions.It is pretty clear that NCDs has its roots in unhealthy lifestyles or adverse physical and social environments. Risk factors like unhealthy nutrition over a prolonged period, smoking, physical inactivity, excessive use of alcohol, and psychosocial stress are among the major lifestyle issues. Now to our understanding, it is known that what has to be done so we have to work more on how to do it (Aulikki et al, 2001). Well planned community programmes can be a succeederful step towards this process. Several factors like cultural, psychological, political and economic factors has created a gap between what needs to be done and day to day happening in the developing countries because of which major health challenges cannot be achieved. So, a community programme will help in bridging this gap and also helps in changing the NCD related lifestyles (Ibid). .The policies made at an planetary level also require global processes which can help to achieve a stable policy change at a country level, thus reducing the long term harm associated with it. Internation al law is an example for this type of process. Multilateral agreements contain legally binding obligations, such as the WHOs Framework Convention on Tobacco Control (FCTC). FCTC includes hard law conventions. FCTC is an evidence-based treaty that identifies core areas of agreement over regulatory measures that have-to doe with countries are leally required to implement within their own domestic systems (WHO, 2005). Apart from FCTC, there are some soft law resolutions and declarations too, like United Millennium Declaration and WHOs Global Strategy on Diet, Physical Activity and Health (GSDPAH). WHO also worked in the area of chronic, lifestyle related diseases through Global Strategy on Diet, Physical Activity and Health (GSDPAH, 2004). It whole caboodle on a strategy which builds on the role of tobacco, unhealthy diet and physical inactivity in the most NCDs. GSDPAH works in close relation with the UN agencies, the WTO, World Bank, other knowledge banks, Codex Airentarius Commis sion (WHO, 2004). One of the most significant health development programs within the United Nations system is the Millennium Development Goals (MDGs). The MDGs are a global partnership embracing ambitious goals to be achieved collectively within 15 years timeframe from 2000-2015 (Magnusson, 2007, p 6). The MDGs and FCTC serve as helpful models when considering ways of strengthening the global response to non-communicable diseases.The ideal step for developing countries to overcome the NCD epidemic and they have to plan and implement accordingly to control NCDs. from apiece one community based prevention programmes require the same principles to be followed. As an example, The magnetic north Karelia Project in least developed areas of Finland which was based on low cost lifestyle modifications and community participation (Puska P et al, 1981). The reason to follow the general principle can be the collaboration between countries and different international organizations working on the similar fields and projects like WHOs countrywide Integrated Non Communicable Disease Intervention (CINDI, 1985). Even these sort of integrated programmes like CINDI were implemented in developed countries they are now followed by the developing countries too. Many of these programmes are carried out in conjunction with the WHO integrated programmes, which was started in 1986. After the success of CINDI programme, American regional office had also launched CARMEN (AMRO) programme in 1990s. With the regional development experience, WHO has launched similar programme in Asian and African networks.In Latin America, Cuba is carrying out the NCD prevention programme from long time with the collaboration with the WHO activities where Havana and Cienfuegos as the main sites. Chile also participated in the Interhealth Programme CARMEN and was the first Latin American country to join this programme and many other countries followed it. Argentina has started PROPRIA heart health intervent ion as an active network at divers(a) demonstration sites (Aulikki, 2001).Africa has started community based CVD prevention programme long time back. Nigeria, Mauritius and united republic of Tanzania participated in Interhealth Programme and gained the positive responses. Mauritius intervention programme preserve considerable effect of nutrition policy and education interventions on diet and serum cholesterol levels, although rates of obesity and diabetes increased (Dowse G et al, 1995).Asias community-based initiatives have been initiated in Sri Lanka, Thailand, Singapore, India, Pakistan, Malaysia, Iran and other countries. Particularly active development has taken place in China, where the Interhealth Programme was involved in initiatives in Tianjin and Beijing (Tian et al, 1995) .The Tianjin project in China was one of the major project launched in 1984 in China. This project was also cooperating groups in Finland, China and USA for NCD control since 1989. This project focuse d on 4 leading NCDs of China, i.e. stroke, coronary heart disease, cancer and hypertension. The aim of this project was to reduce sodium intake in the population, decrease smoking especially among men and provide hypertension care by reorganizing the existing primary health care services. The result of this project shows a significant reduction in the sodium intake after three years and also reduction in number of patients of Obesity and hypertension among 45-65yrs old after five years of the intervention. Smoking cases were also reduced among men, especially those with the higher education (Aulikki et al, 2001).Health education and the media campaigns also play an important role in the community programmes. Media campaigning although leaves the less impact on the population, it is one of the effective measure in the comprehensive package. Health service intervention such as primary care centre in the long run can also be one of the most effective intervention tools. This strategy c an more appropriately work where veritable biological risk factors such as hypertension and high blood pressure are dealt with. Primary health care workers played an important role in both North Karelia project and Tianjin project (Ibid).The North Karelia project worked on a concept of Community organization where various sectors of the community were collaborated and involved. It involved many non governmental organizations (NGOs), such as Housewives organizations. It is not easy to collaborate with the industries and businesses at a small community but a classic example for it is finlands cholesterol level, which reduces with the support and collaboration of the food industries, who supported the policy decisions (Puska P et al, 1986).Aulikki et al had made some recommendations for a successful NCD prevention program which must include the following factors. A good understanding of the community, close collaborations with the various community organisations and the involvement o f the local population is important for any community intervention programme. It should combine well planned media and provide some communication messages in the community activities. It should involve different elements such as primary health care workers, food industries and supermarkets, voluntary organisations, schools work places, and local media for its success. It should be cost effective, mainly in the developing countries. For this reasonable outcome, effective dose intervention is a very important requirement (Aulikki et al, 2001).The increasing NCDs burden should be controlled by the developed and developing countries as a global health priority. International organisations with the national, regional and each individuals contribution can make these programme a success. Controlling of risk factors like smoking, alcohol, obesity, diet and inactivity, sexual and environmental factors are must and should be considered severely and worked upon to treat it. The poverty and th e high cost of prevention and treatment of chronic diseases causes burden on many countries and thus demands for international solidarity and public private partnership. The coordination of health decision makers, non-governmental organizations, research institutions, community groups and individuals is must for controlling the incidence of diseases, preventing the spread of epidemics and regulate the health management of human and material resources (Boutayeb, 2005). WHO is a political hero for coordinating global response. The developing countries face problem in the implementation and enforcing the policies that are set up by the international legal standards which have a normative role and also these legal standards are not self executing, so compliance can be monitored by the NGOs and government. A global draw close in a way like this could reduce health inequalities (Magnusson, 2007).REFERENCES Anand K, Shah B, Yadav K, Singh R, Mathur P, Paul E, Kapoor S K (2007), Are the u rban poor vulnerable to non-communicable diseases? A survey of risk factors for non-communicable diseases in urban slums of Faridabad, The National Medical Journal of India, Vol. 20, No. 3, p 115-120. Aulikki Nissinen, Ximena Berrios, Pekka Puska (2001), Community-based non-communicable disease interventions lessons from developed countries for developing ones, Bull World Health Organvol.79no.10. Beaglehole R, Yach D (2003), Globalization and the prevention and control of non-communicable disease the neglected chronic diseases of adults, The Lancet 362 903-08.* Boutayeb Abdesslam (2006), The double burden of communicable and non-communicable diseases in developing countries, Royal Society of equatorial Medicine and Hygiene, Volume 100, Issue 3, scalawags 191-199 . Countrywide integrated non-communicable diseases intervention (CINDI) Programme. Copenhagen, WHO, Europe, 1995.* Dowse G (1995), Changes in population cholesterol concentrations and other cardiovascular risk factor level s after five years of the non-communicable disease intervention programme in Mauritius, British Medical Journal, 311 12551259.* Ezzati M, Lopez A (2003), Estimates of Global Mortality Attributable to Smoking in 2000. TheLancet, 362847-852.* Guindon G, Boisclair D (2003), Past, Current and Future Trends in Tobacco Use-Health, Jamison D, Breman J, Measham A, Alleyne G, Claeson M, Evans D (2006), Priorities in Health, Washington DC, World Bank. Horton Richard (2005), The neglected epidemic of chronic disease, The Lancet, Volume 366, Issue 9496, Page 1514.* Lee K, Fustukian S, Buse K (2002), An Introduction to Global Health Policy, Health Policy in a Globalising World, Cambridge, Cambridge University Press 20023-17.* Leeder S, Raymond S, Greenberg H, Liu H, Esson K (2004), A Race Against Time The contend of Cardiovascular Disease in Developing Economies, New York, Columbia University.* Magnusson R S (2007), Open Access Non-communicable diseases and global health governance enhancing gl obal processes to improve health development, Globalisation and health 32. (http//www.globalizationandhealth.com/content/3/1/2).* Mehan M B, Srivastava N, Pandya H, (2006), Profile of noncommunicable disease risk factor in an industrial setting, J Postgrad Med52167-173.* Miranda J J, Kinra S, Casas J P, Smith G D , Ebrahim S (2008), Non-communicable diseases in low- and middle-income countries context, determinants and health policy, Trop Med Int Health 13(10) 1225-1234. (http//www.ncbi.nlm.nih.gov/pmc/articles/PMC2687091).* Murray J L and Lopez A D (1996), The global burden of disease a comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020, Harvard School of Public Health, Cambridge, MA. Puska P (1981), The North Karelia Project Evaluation of a comprehensive community programme for control of cardiovascular diseases in North Karelia, Finland, 1972-1977, Copenhagen, WHO, Europe.* Semenciw R M, Morrison H I, Mao Y, Johansen H, Davies J W , Wigle D T. (1988), Major Risk Factors for Cardiovascular Disease Mortality in Adults Results from the sustentation Canada Survey Cohort, International Journal of Epidemiology, Vol.17, No.2, p 317-324. Reddy K S (2002), Cardiovascular diseases in the developing countries dimensions, determinants, dynamics and directions for public health action, Public Health Nutrition 5, pp. 231-237. WHO (2002), Reducing Risk Promoting Health Life, World Health Organization, Geneva, Annual Report.* WHO (2003b), Diet, Nutrition and the prevention of Chronic Diseases, World Health Organization, Geneva, Technical Report Series No. 916. WHO (2004), Global Strategy on Diet, Physical Activity and Health, WHA57.17. WHO (2005), WHO Framework Convention on Tobacco Control, WHA56.1* Yusuf S, Reddy K S, Ounpu S, Anand S (2001), Global burden of cardiovascular diseases Part I General considerations, the epidemiological transition, risk factors, and impact of urbanization, Circulation 1
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